Director, Bioinformatics

Company: Ambry Genetics
Location: Aliso Viejo
Posted on: June 24, 2022

Job Description:

Title: Director, Bioinformatics Location: Remote Job Overview:The job's main responsibility is to lead a bioinformatics team to collaborate with cross-functional departmental teams to build and integrate cutting edge computational solutions and applications to improve clinical diagnostics. With both technical and leadership capacities, the Director of Bioinformatics will drive bioinformatics strategy and initiatives in support of Ambry's mission.JOB RESPONSIBILITIES:1. Provide strategic input and leadership in analyzing and interpreting next generation sequence data, and execute research plans2. Design, coordinate and oversee the execution of the bioinformatics software. Mission in collaboration with project teams within the company from sample receipt to data delivery, such as assay research and development and production operations in the CLIA laboratory.3. Ensure high quality data and compliance with regulatory guidelines for analyses of next generation sequencing data4. Ensure that the bioinformation system in laboratory operations is routinely working to the highest standard, including consistently evaluation of the performance, designs and pipelines5. Maintain and expand expertise in various bioinformatics analysis algorithms and computing tools to leverage internal and external data sets to derive decisions6. Work cross functionally with all stakeholders, including seek input and review proactively, prioritize projects and actively drive continuous improvement7. Lead research teams by providing expertise in study design, execution, and analysis and coordinate with laboratory, clinical diagnostics teams and collaborators from academic, hospital and healthcare industry8. Lead and manage the bioinformatics and computational biology team with scientists and software engineersMANAGERIAL RESPONSIBILITIES: - Size of Team: 5-20JOB REQUIREMENTS: - PhD degree in bioinformatics, biostatistics, computational biology, biophysics, biology and computer science, or related discipline plus at least 6 years postdoc/industrial experience - MS degree in bioinformatics, computational biology, biophysics, biology and computer science, or related discipline plus at least 8 years industrial experience - Strong knowledge of current theories and principals of structural biology, statistical genetics, molecular biology, biological pathways, genomics, bioinformatics and computational biology - Proficiency in bioinformatics and statistical tools, software, packages, and database - Proficiency in statistical/mathematical modeling, computational algorithms, data mining and machine learning - Proficiency in programming language and software application development, such as Perl, Python, R, SAS, bash, C/C++, java, and SQL in Linux/Unix environment - Proficiency in utilizing and development biomolecular structural modeling and dynamics tools - Proficiency in applications of statistical analytical methods in genetic data analysis - Extensive experience with molecular biology procedures and next generation sequencing instruments - Extensive experience implementing and documenting workflow management systems, protocols, standard operation procedures, and quality control processes - Proven success in managing a team of scientists and software engineers performing molecular biology laboratory data analysis and clinical research - Ability to work within a team, among cross-departments with colleagues with diverse backgrounds and contribute to team goals. - Excellent verbal and written communication skills - Experience in production software development, testing, and deployment - At least 8 years of experience in research and development in related fields - At least 8 years of experience in building and managing scalable computational tools in high throughput environment, including large data volume applications using high performance computing and storage systems - At least 6 years of experience in management of scientists and software engineers with strong team mentorship skills - At least 4 years of experience in creating and maintaining software for clinical diagnostic products (CLIA or FDA)About Us Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster.At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community.At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas. Our outstanding benefits program includes medical, dental, vision, 401k, FSA, and generous paid time off (PTO) program. Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment.Ambry Genetics is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race (and traits historically associated with race, including, but not limited to hair texture and protective hairstyles such as braids, locks, and twists), color, creed, religion, sex, sexual orientation, gender identity, gender expression (including transgender status), national origin, ancestry, age, marital status or protected veteran status and will not be discriminated against on the basis of disability, protected medical condition as defined by applicable state or local law, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances.Ambry does not accept unsolicited resumes from individual recruiters, third party recruiting agencies, outside recruiters or firms without an executed contract in place. We are not responsible for any fees related to resumes that are unsolicited or are received by Ambry. Such resumes will be deemed the sole property of Ambry and will be processed accordingly.

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